Friday, May 18, 2007

Soloxine Precautions

Soloxine should not be used in animals allergic to it. Do not use in animals with untreated adrenal insufficiency (Addison's disease), use with caution in animals with high blood pressure. Use with caution when given with warfarin, theophylline, digoxin, phenytoin and barbiturates. Give 1 hour before or 4 hours after vitamin/mineral combinations containing iron or calcium. Always tell your veterinarian and pharmacist what other medications your pet is taking. There can be differences in the action of levothyroxine when changing brands. As a result, it may be necessary to retest T4 levels when switching brands

What are Soloxine Tablets?

Soloxine tablets are also known as Levothroxine Sodium Tablets, USP.

Levothyroxine sodium acts, as does endogenous thyroxine, to stimulate metabolism, growth, development and differentiation of tissues. Levothyroxine sodium is absorbed rapidly from the gastrointestinal tract after oral administration. Following absorption, the compound becomes bound to the serum alpha globulin fraction. For purposes of comparison, 0.1 mg of levothyroxine sodium elicits a clinical response approximately equal to that produced by one grain (65 mg) of desiccated thyroid. Soloxine is available in uniquely shaped, color coded tablets in eight different strengths to allow easy and convenient dosage adjustment.

Soloxine provides thyroid replacement therapy in all conditions of inadequate production of thyroid hormones. Soloxine (Levothyroxine Sodium Tablets, USP) will provide levothyroxine (T4) as a substrate for the physiologic deiodination to liothyronine (T3). Administration of levothyroxine sodium alone will result in complete physiologic thyroid replacement.

Soloxine Side Effects

If Soloxine is given at the proper dose as determined by blood tests there should be no side effects. Overdose will result in the symptoms of thyrotoxicosis which may include increased thirst, urination and hunger, hyperactivity, personality change, and reduced heat tolerance.

If your pet has been put on Soloxine by your vet, it may be used on a long-term basis. Because this drug may have other affects, you may want to monitor your pet's health periodically. This may require periodic exams or blood tests to check thyroid levels.